Saadia Khaleeq, Abaid-ur Rehman, Sanna Fauzan, Sana Siddiq, Mohammed Aazam, Zulqarnain Butt, Naila Akhter.
A Comparative study between Dexmedetomidine and Magnesium Sulphate as Adjuvants with Ropivacaine in Caudal Blocks in Pediatric patients for Infraumblical Surgeries.
Pak Paed J Jan ;44(3):230-5.

Objective: Pediatric caudal block is a simple, reliable and safe analgesic technique for infraumblical surgeries but having disadvantage of short duration after single injection. Different additives were combined with local anesthetics to enhance the duration and quality of block. We designed this study to compare Dexmedetomidine and Magnesium Sulfate as adjuvants to Ropivacaine for pediatric caudal block. Study Design: Randomized, Controlled Trial. Duration & Place Of Study: Six months from 1-11-19 to 30-4-20. SIMS Medical College/Services Hospital Lahore. Materials and Methods: Sixty children meeting our inclusion criteria were randomly assigned into two groups RD and RM after obtaining informed consent from their parents. After induction of anesthesia, each patient received single caudal dose of Ropivacaine combined with either Dexmedetomidine or Magnesium Sulphate. Postoperative analgesic duration, time to first analgesic request and postoperative complications were noted. Results: There is no significant difference in Face, Legs, Activity, Cry and consolability (FLACC) pain scoring in both groups till 2 hours postoperatively. However, it became significantly high after 6,12 and 18 hours in Group RM. Time for first analgesic demand was significantly longer in Group RD. No significant adverse effects were observed in both groups in first 24 hours. Conclusion: Dexmedetomidine is a better perineural adjuvant in terms of postoperative analgesia in pediatric caudal blocks as compared to Magnesium Sulphate.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com