Ghazanfar Ali Sirhindi, Muhammad Tayyib, Tahira Tasneem, Muhammad Farooq, Nasir Ahmad Chaudhary.
Fibrinogen Degradation Products and Coagulation Parameters in Women Taking Oral Contraceptives.
Ann King Edward Med Uni Jan ;9(3):185-7.

A study plan was designed to estimate the coagulation parameters like Prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen level and fibrinogen degradation products (FDPs). In this study, coagulation parameters were compared in combined oral contraceptives (COCs) and control group. 40 subjects of COCs with 20 normal females without hormonal contraceptive were included in this study. Blood samples were collected for special coagulation parameters. FDPs were significantly elevated in subjects using COCs as compared to normal control. PT and APTT were shortened in COCs. Fibrinogen levels were increased significantly in COCs when compared with control groups.

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