Gagan Priya, Sanjay Kalra, Silver Bahendeka, Fatema Jawad, Than Than Aye, Selim Shahjada, Ashish Sehgal, Andrew Uloko, Sudeep Ruder, Noel Somasundaram, Mohammed Wali Naseri, Sandeep Chaudhary.
Initiation of basal bolus insulin therapy..
J Pak Med Assoc Jan ;70(8):1462-7.

Most practice guidelines recommend the use of long acting or pre-mixed insulin at the initiation of insulin therapy in type 2 diabetes, especially in patients not achieving glycaemic goals. Nonetheless, there are some specific indications where basal bolus insulin is the preferred regimen for insulin initiation. These include the "5S" situations - 'Severe' hyperglycaemia, 'Symptomatic' diabetes, 'Sick' diabetes (acute or chronic comorbidity), 'Special' situations (pregnancy, childhood, adolescence) and 'Secondary' diabetes (pancreatic, drug-induced, endocrine disorders). This review describes a practical approach to initiation and follow up of basal bolus insulin regimens.

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