Javaid Mi, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M, Ahmad R, Anwar A.
Relationship of CD4+ Count with Viral Load in HIV/AIDS patients.
Biomedica Jan ;35(1):41-4.

Background & Objectives: CD4 counts and Viral loads are the parameters which are used to monitor the health status in HIV infected individuals. Viral load affects CD4 counts, as high levels of virus in blood causes reduction in CD4 cell counts leading to symptomatic disease in future. This study was aimed to determine CD4 count, viral load and their possible relationship in HIV patients. Methodology: One hundred six (106) HIV patients had been enrolled in the pathology laboratory. CD4 counts, viral loads were measured and evaluated. Statistics were applied. Association between two parameters was calculated by applying statistical tests. p value of less than 0.05 was considered statistically significant. Results: Of the total 106 patients, there were 83 (78.3%) males, 17 (16%) female patients and 6 (5.7%) trans-gender. Majority of the study population 50/106 (47.2%) had CD4 lymphocyte count >= 500/ul, 38/ 106 (35.8%) cases had CD4 lymphocyte count in the range of 200 - 499/ul, while CD4 lymphocyte count < 200/ul was seen in 18/106 (17%) cases. Reciprocal relationship was observed between CD4 count and viral loads. Statistically significant difference was observed with P-value 0.012 Conclusion: Reciprocal relationship was observed between CD4 count and viral loads.CD4 count and viral loadsare utilized as screening tools to assess the progression and severity of HIV infection.

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