Aakif Ullah Khan, Karim Khan, Ghufran Biradar, Aftab Ali, Moiz Khan.
Photodynamic therapy for conventional treatment resistant acne vulgaris.
J Pak Assoc Derma Jan ;29(3):334-7.

Acne vulgaris is a common chronic inflammatory skin disease, typically affecting young adults and adolescents. Acne vulgaris can leave the patient with severe skin scarring and psychological effects. Photodynamic therapy (PDT) is an increasingly used therapeutic modality for various diseases in dermatology. In this study we used PDT to treat acne vulgaris, which developed resistance to conventional treatments. A 25-years old female patient presented with facial acne vulgaris. The patient had received conventional treatments for the last 7 years, with no satisfactory outcome. The patients was treated with methyl aminolaevulinate based PDT in three sessions; the first two sessions were repeated at two weeks interval, while the third session was given at one month interval. After 3 months of treatment, the patient response to the treatment was assessed at 95%. The patient was followed up to 6 months and no recurrence has been observed. MAL-PDT has a rapid response, excellent cosmetic outcomes and significantly effective for improving acne lesions.

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