Hazim Brohi, Ayisha Farooq, Bushra Rehan, Muhammad Mairaj Khan.
Cerebral cavernous malformation presenting as seizures.
Pak J Neurological Sci Jan ;15(3):27-30.

Background: Cerebral cavernous malformations (CCMs) is one of the rare vascular malformation. It is diagnosed by characteristic lesions on magnetic resonance imaging (MRI). CCMs typically appears as a “popcorn-like” masses on T2-weighted images on MRI studies. And clinically can lead to headaches, seizures, focal neurological deficits or intracerebral hemorrhages. . A familial form is suggested if lesions are multiple, and a sporadic form, if single Case presentation: This case report involves Status epilepticus in a 45-year-old male was brought to the Emergency department with a history of headache for 2-3 days and seizures lasting 2 hours. MRI showed multiple rounded lesions suggestive of heamorrhagic lesions. These lesions consist of a mixed signal intensity core accompanied by a hypointense hemosiderin rim. Patient was intubated and started on intravenous anti epileptics (midazolam 5mg) along with propofol along with antiepileptics. Fits subsided and propofol was eventually stopped and he was extubated and went back home. Conclusion: Summing up our patient presented with seizures secondary to cerebral cavernous malformations probably familial as the lesions on MRI were multiple. This is a rare entity and these patients require a close follow up and all the family members must be screened and treated.

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