Humaira Maryum Agha, Krishan Lal, Sadaf Ahmed Asim, Yasmin Channa, Farah Saleem.
Frequency of Helicobacter pylori antigen in stool of patients with chronic urticarial.
Rawal Med J Jan ;45(3):523-6.

Objective: To determine the frequency of Helicobacter pylori antigen in stool of patients with chronic urticaria who presented at our tertiary care hospital. Methodology: This descriptive cross-section study was carried out at department of dermatology in collaboration with department of pediatrics, Al-Tibri Medical College & Hospital and Isra University Karachi Campus, during a period of one year. Patients with chronic urticaria of both genders and all ages were selected by non-probability convenience sampling. Patients with known co-morbidities and other causes of urticaria as well as those with acute urticaria were excluded. Results: Out of 116 patients, 73 had positive H. pylori antigen in their stool. Females patients (67.2%, n=43) and those who had angioedema (66.7%, n=16) were more likely to have H. pylori antigen positive. Serum level of immunoglobulin E was found quite elevated in patients who were positive for H. pylori antigen. Conclusion: Considerable number of patients with chronic urticaria had H. pylori antigen in their stool. This antigen is internationally recognized to be the cause of chronic urticaria in many countries.

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