Jamshed Ali, Faryal Ali, Arsalan Khan, Muhammad Junaid.
Pharmacological screening of hypericum oblongifolium for its analgesic effect in mice.
J Med Sci Jan ;28(3):260-4.

Objective: The present study investigates the anti-nociceptive activity of crude methanol extract of Hypericum oblongifolium. Methods In vivo acetic acid induced writhing test was used for anti-nociceptive effects at 10mg, 20 mg and 30 mg/kg body wt. respectively intraperitoneally. Results: The extract doses of 10, 20 and 30 mg/kg i.p. revealed significant inhibitory effect (P < 0.001) in acetic acid induced writhing test. Conclusions: The methanol extract of medicinal plant Hypericum oblongifolium showed significant analgesic / anti-nociceptive effects in animal models and thus validates the traditional uses of the plant in painful conditions.

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