Quratulain Saeed, Sarwat Memon, Mervyn Hosein, Sana Ikram.
Clinical Correlation of Periodontal Disease Parameters with Crevicular Blood Glucose Levels.
J Pak Dent Assoc Jan ;30(1):12-7.

OBJECTIVE: The purpose of the study was to assess relationship between the clinical periodontal parameters and gingival crevicular blood glucose levels and to determine the relation of severity of periodontitis with glycemic levels. METHODOLOGY: A total number of 348 patients with chronic periodontitis participated in this cross-sectional study. After recording the number of teeth and plaque percentage, the participants were assessed for severity of periodontitis according to clinical periodontal parameters of periodontal pocket depth, gingival recession, clinical attachment loss and gingival bleeding. Gingival crevicular blood glucose was assessed via glucometers and random blood glucose levels were recorded for each patient. SPSS version 20 was used for data analysis. The correlation between periodontal parameters and glycemic levels was assessed via Pearson`s correlation coefficient. Multiple regression analysis was used to predict the association of glycemic levels with periodontal parameters. Analysis of variance was used to compare the glycemic levels in patients with mild, moderate and advance periodontitis. RESULTS: Age, bleeding on probing and clinical attachment loss showed significant positive correlation while number of teeth showed significant negative association with crevicular blood glucose levels. Multiple regression analysis indicated that crevicular blood glucose has significant linear association with bleeding on probing and clinical attachment loss. Gingival crevicular blood glucose levels were found to be increasing with severity of periodontitis. There was significant difference (p<0.001) in mean glucose levels between mild, moderate and advanced periodontitis groups. CONCLUSION: Clinical periodontal parameters and severity of periodontitis are strongly associated with increasing gingival crevicular blood glucose levels.

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