Muhammad Zeeshan Khan, Anjum Saeed, Fariha Ahmad Khan, Fawad Ahmad Khan, Attia Bari, Samreen Ashraf.
Efficacy of Clinical Scoring in Diagnosing Malaria in a Developing Country: a Cross-Sectional Study.
Pak Paed J Jan ;44(4):320-3.

Objective: To validate the clinical scoring system for malaria in children devised in India and express the clinical significance. Study design: Cross sectional study. Place and Duration of Study: This study was conducted from August-November 2016 at the Children`s Hospital, Lahore. Material and Methods: Every febrile child between the age of 1-15 years admitted in hospital or presented in outdoor fulfilling the case definition of suspected malaria was included. Results: Mean clinical score in proven and non-proven malaria cases were 11.38 and 7.41 respectively with p-value of <0.001. At score value of > 8.8, area under curve (AUC) was 0.937 (95% CI 0.879-0.995) with p-value of <0.001. All positive malarial cases (n=26) diagnosed by rapid diagnostic test (RDT) had a mean score of 11.38 ? 1.76, while mean score of 7.41 ? 1.86 was documented in negative (n=46) cases. Conclusion: Our study validated the clinical scoring system for malaria in children with high impact and can be applied in resource limited countries like Pakistan.

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