Rehma Dar, Salma Haq, Maria Aslam.
Effect of BMI on soluble intercellular adhesion molecules in type 2 diabetics with microvascular complications.
J Sharif Med Dent Coll Jan ;2(01):10-2.

Objective: To compare the levels of soluble Intercellular adhesion molecules (sICAM-1) in obese and nonobese Type 2 diabetics with microvascular complications. Methodology: The study included 40 patients with type 2 diabetes mellitus with microvascular complications. They were further divided into two groups. Group A included 20 patients with body mass index (BMI)>25 Kg/m2 and group B had 20 patients with BMI<25 Kg/m2. Levels of SICAM-1 were measured by Enzyme linked immunosorbent assay in both groups. Results: Mean value of the SICAM-1 levels were 1408.05 + 525.29ng/ml in group A and 767.35 + 113.93ng/ml in group B. A significant difference was seen when levels of sICAM-1 were compared between two groups (p<0.05). Conclusion: sICAM-1 levels were high in obese type 2 diabetic patients with microvascular complications than in non obese type 2 diabetic patients with microvascular complications. Keywords: Type 2 diabetes mellitus. SICAM-1. Body mass index.

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