Ihsan-ul Haq Zarkoon, Wazir Akbar, Noor Ahmed Khosa.
The MIDAS score after Memantine in patients with migraine at a tertiary care Hospital.
Pak J Neurological Sci Jan ;16(1):26-9.

INTRODUCTION: Memantine has been suggested as a migraine prophylaxis therapy in some observational studies. OBJECTIVE: To determine the mean change in MIDAS score after Memantine in patients having migraine. SAMPLING TECHNIQUE: Non-probability, consecutive sampling. Methods: This study was conducted in the Neurology department, Bolan Medical Complex Hospital, Quetta. January 2017 to January 2018. All patients in the outpatient department of Bolan medical complex hospital, Quetta, with the diagnosis of migraine were enrolled in the current study after informed consent. RESULTS: A total of 68 patients with a mean age of 32.32 ± 8.44years were enrolled in the study. Gender distribution of the patients showed that most of the patients were female. Most of the patients had a duration of symptoms of >3± 2.11 years. Before starting treatment, the mean MIDAS score was age group 18-30 years 43.53 ± 13.36 and at the end of treatment was 9.86 ± 6.28 (P=0.005). 31-45 years age group before MIDAS score was 43.73 ± 8.83 and treatment after MIDAS score 9.31±3.36. The difference in MIDAS scores before and after treatment was assessed. CONCLUSION: The current small cohort has been effective in predicting that the use of Memantine may lead to the improvement in MIDAS score regarding the management of Migraines; however, large-scale studies are needed to validate this current study's results further.

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