Anam Anis, Iqra Athar, Mazhar Badshah.
Association of supine hypertension in patients with Parkinson\\\'s disease.
Pak J Neurological Sci Jan ;16(1):16-20.

INTRODUCTION: Parkinson’s disease is a neurodegenerative disease affecting older age populations. There is variable evidence of its relationship with hypertension. To date most of the studies have targeted orthostatic hypotension, however, rare data regarding supine hypertension has been witnessed so far. This study aimed at determining the association of supine hypertension with Parkinson’s disease. Methodology: A retrospective observational study was conducted at the Department of Neurology, Pakistan Institute of Medical Sciences, Islamabad. Medical records of 32 patients with Parkinson’s disease were reviewed. Data included baseline, clinical and therapy information along with presence of supine hypertension. Ethical clearance was taken and administrative permission was granted by HOD. Study outcome was measured in terms of relationship of supine hypertension with Parkinson’s disease. Results: Male gender (75.0%) and older age than 60 years (56.2%) was predominantly affected with PD. Almost one third patients had known hypertension 9 (28.1%) out of which 7 (21.9%) are on ARBs. There were 5 (15.6%) patients on beta blocker, 1 (3.1%) was having calcium chain blocker and 2 (6.2%) diuretics. Out of total 68.9% patients had supine hypertension. Duration of PD was found greater in patients with supine hypertension. Conclusion: Supine hypertension is significantly associated with Parkinson’s disease, especially found in patients with longer duration of disease.

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