Iqra Athar, Neelma Naz Khattak, Haris Majid Rajput, Mazhar Badshah, Zukhruf Zayian, Tashfain Shifa.
Finger Drop Sign in Guillain-Barre Syndrome.
Pak J Neurological Sci Jan ;16(1):10-5.

BACKGROUND: Guillain-Barre syndrome (GBS) is a post-infectious, immune-mediated disease that causes a rapidly progressing poly-radiculoneuropathy resulting in weakness and areflexia. It has several variant forms like AIDP, AMAN and AMSAN. Objective: To determine frequency of finger drop sign in AMAN and AIDP variant of GBS; a diagnostic factor of AMAN variant. Material and Methods: A Cross sectional study conducted at neurology department of Pakistan Institute of Medical Sciences. After meeting the inclusion criteria 96 patients were enrolled. Clinical assessment was done i.e. power of the patient was checked and recorded according to the MRC sum score, finger drop sign was checked at time of presentation and NCS was done and variant of GBS noted. The data thus collected was entered on a standardized Performa. Results: The mean age of the patients was 42.04±18.97 years, 66(68.75%) patients were males. At presentation the mean MRC sum score of the patients was 33.91±9.86 while at discharge the mean MRC sum score of the patients was 45.27±13.36. AMAN variant of GBS was noted in 35(36.46%) patients and AIDP variant of GBS was noted in 61(63.54%) patients. Comparison of finger drop with variant of GBS showed significant difference (p-value<0.05). Conclusion: According to this study approximately one third of the patients had AMAN variant and two third of the patients had AIDP variant of GBS. In AMAN variant the finger drop noted in all patients.

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