Rafia Irum, Maliha Yousaf.
Diagnostic Accuracy of Ultrasonography in Diagnosing Acute Pancreatitis, Taking Computed Tomography as Gold Standard.
J Sharif Med Dent Coll Jan ;7(01):30-6.

Objective: To determine the diagnostic accuracy of ultrasonography (USG) in diagnosing acute pancreatitis taking computed tomography as gold standard. Methodology: It was a cross-sectional study conducted from September 2020 to February 2021 at the Department of Radiology, Sharif Medical & Dental College, Lahore. A total of 156 patients of both genders between 15-55 years and with a duration of disease <2 weeks were included in the study. Patients presented with symptoms of acute pancreatitis like sudden onset abdominal pain, fever (>101F), tachycardia (heart rate >120/min), and serum amylase >400U/L were taken as positive symptoms and included in this study. Patients with history of abdominal trauma, hypersensitivity history to iodinated contrast agent, chronic kidney failure, claustrophobic patients, and patients unable to undergo Computed Tomography (CT) scanning were excluded from the study. After taking informed consent, ultrasonography (USG) of hepatic-biliary system was performed by the consultant radiologist and was looked for presence or absence of acute pancreatitis as pre-operational definition. All patients underwent CT scan and reports were interpreted by the radiologist. Ultrasonographic findings were compared with CT scan findings. Results: Ultrasonography supported the diagnosis of acute pancreatitis in 71(45.51%) patients. Computed tomography findings confirmed acute pancreatitis in 81(41.67%) cases. In USG positive patients, 59 were true positive and 12 were false positive. Among 85 USG negative patients, 06 were false negative whereas 79 were true negative (p=0.0001). Overall sensitivity, specificity, positive & negative predictive value and diagnostic accuracy of ultrasonography in diagnosing acute pancreatitis taking computed tomography as gold standard was 90.77%, 86.81%, 83.10%, 92.94% and 88.46% respectively. Conclusion: Ultrasonography is a highly sensitive and accurate non-invasive method in diagnosing acute pancreatitis. Keywords: Acute pancreatitis. Ultrasonography. Sensitivity. Specificity.

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