Nauman Al Qamari, Amjad Sattar, Hatem Adel.
Health related quality of life (HRQOL) in patients undergoing trans-arterial chemo-embolization for unresectable hepatocellular carcinoma.
Pak J Radiol Jan ;28(2):104-8.

OBJECTIVE To determine the health related quality of life in patients undergoing transarterial chemoembolization (TACE) for hepatocellular carcinoma METHODS A before and after survey was conducted from February 2014 till December 2015 and all patients who underwent TACE irrespective of age and gender with at least one follow up at or after 06 weeks were included. Patients who lost to follow up were excluded. Short form 12 questionnaire was used to assess health-related quality of life before and after TACE. These information along with demographic of the patients like age, gender, duration of follow-up, bilirubin level, tumor size and child score was calculated. RESULTS Out of total 53 patients, female preponderance was found to be higher 42 (79.2%) than that of males 11 (20.8%). Majority of the patients were had hepatitis C 47 (88.7%) whereas hepatitis B infection was found in 6 (11.3%) patients. Majority of the patients were presented with child score B 34 (64.2%) followed by child score A 17 (32.1%) whereas only 2 (3.8%) patients were presented with child score C. Significant difference was observed in the physical and mental quality of life before and after TACE, i.e. 45.3 (42.2-47) vs. 46.2 (44.2-47.2), p-value <0.001 and 52.3 (48.9-54) vs. 56.3 (53.4-58.9), p-value <0.001 respectively. CONCLUSION Significant improvement in physical and mental health related quality of life was observed in patients suffering from hepatocellular carcinoma undergoing TACE.

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