Fiza Shaheen, Muhammad Amer Awan, Aiman Hafeez, Aqdus Haq, Ramsha Zainab Malik.
Incidence of endophthalmitis following intravitreal anti VEGF injections at a tertiary care hospital in Pakistan..
J Pak Med Assoc Jan ;71(4):1184-8.

To assess the rate of infectious endophthalmitis with anti-vascular endothelial growth factor injection, and to evaluate institutional procedure protocol in this regard. The retrospective consecutive case series was conducted at Shifa International Hospital, Islamabad, Pakistan, from August 2018 to January 2019, and comprised 5-year data from August 2014 to July 2019 related to patients who underwent intravitreal anti-vascular endothelial growth factor injections. Data was analysed using SPSS 21. Of the 7,542 injections administered to 2,734 patients, 5,976(79.2%) were bevacizumab, 1,081(14.3%) ranibizumab and 485(6.4%) aflibercept. There was 1(0.01%) case of infectious endophthalmitis which was treated with 25 gauge pars plana vitrectomy. The institutional procedure protocol was found to be effective as the rate of infectious endophthalmitis was lower than what is reported in literature.

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