Alidina A, Siddiqui T, Burney I, Jafri W, Hussain F, Ahmed M.
Esophageal Cancer - a review.
J Pak Med Assoc Jan ;54(3):136-41.

Esophageal cancer is a highly virulent malignancy, where the overall cure rate is <10%. At presentation, systemic disease is found in over 50% of the cases, leading to incurability. Of the patients that present with locoregional disease, most will relapse with the primary therapy, leaving the cure rate in this group to 12-35%. The most commonly accepted standard of care for localized disease is surgical resection. Neoadjuvant chemoradiotherapy given as a combined modality therapy leads to pathological responses to 20-40%, which could be the surrogate markers to cure. Newer agents and targeted therapies will have an important role in the care of esophageal cancer. This is a review article.

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