Naeem-ul Haq, Muhammad Ishaq, Musawer Khan, Adnan Ahmed, Gohar Ali.
Surgical Outcome of Transpedicular Fixation for Degenerative Spondylolisthesis in Terms of Relief from Backache.
Pak J Neuro Surg Jan ;25(3):406-13.

Objective:  To document the outcome of transpedicular fixation for degenerative spondylolisthesis in terms of relief from backache. Materials & Methods:  This retrospective observational study was conducted in Mardan Medical Complex, Mardan. Static and dynamic spinal X-rays were used to diagnose degenerative spondylolisthesis. This research looked at how patients' pain levels, neurological state, and union improved after surgery. Patients with grade 5 spondylolisthesis, having congenital spinal anomaly, or who had previous spinal surgery were excluded from the study. Results:  In total 35 patients were included, 54.3% were male and 45.7% female. The primary reason for surgery was severe backache with 24 individuals having normal neurological status and 11 patients having some neurological abnormality. L5–S1was the most commonly involved level in 24 patients. Meyerding grades were used to determine the slip grade. The average duration of follow-up was two years and five months, with a maximum of five years and a minimum of six months. 83 percent of patients had pain reduction, whereas neurological improvement was achieved in 64 percent of instances and surgical union was achieved in 91 percent of cases. There was no neurological impairment in the patients treated with transpedicular fixation. Significant differences exist between preoperative and postoperative GRS scores in the following pain categories: no pain, mild, server and excruciating. Conclusion:  Transpedicular fixation is a protected, simple, and successful procedure for patients with spondylolisthesis for pain relief in backache. It also contributes to surgical union and improvement in the neurological status of the patients.

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