John S Isaac, Navid R Qureshi, Usha Isaac.
Oral Lichen Planus: A study of 150 cases.
Pak Oral Dental J Jan ;23(2):145-150.

A study of oral lichen planus on 150 extending over 30 years was undertaken, a female predominance was noted. Most patients (47.3%) were from the intermediate and non manual worker class. The buccal mucosa (89.3%) followed by the gingival (39.3%) were found to be the most commonly affected sites. Soreness featured as the most common presenting complaint (56.6%). The keratotic lesion was the most frequent type. A history of chronic disease was noted in 79 patients while 22 of 91 patients (53%) investigated for surgical episodes gave a history of surgical episode within one year of onset. History of prolonged use of drugs was noted in 73 patients. Use of tobacco was noted in 43. Alcohol consumers totaled 79. Stress at onset was recorded in 105 patients. Denture wearers were noted at 38. Heavily restored teeth were recorded in 48 of 111 patients. Biopsy report was found to be consistent with clinical diagnosis in 108 patients out of 123 investigated while 15 reported non diagnostic lesions. Candidal infection was investigated in 68 patients (45%) and 34 (50%) were noted positive. Sideroperia was detected in 16 female patients (24.6%) out of a total of 97 patients in whom 65 were females. No iron deficiency was noted in males. Vitamin B12 deficiency was noted in 4 (5.3%) out of 75. Remission was noted in 4 patients and familial lichen planus was noted on two occasions. Malignant transformation was recorded at 2 percent.

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