Ammarah Afreen, Zarah Afreen, Sadia Daaniyal, Shoaib Rahim, Aamna Khalil, Umer Javed.
Comparison of the Effect of Ledermix Paste and No Intracanal Medicament on Interappointment Pain During Root Canal Therapy.
J Islamic Int Med Coll Jan ;16(3):156-60.

Objective: To compare the mean interappointment pain using Ledermix paste and no intracanal medicament in patients with acute apical periodontitis. Study Design: Randomized controlled trial. st Place and Duration of Study: Operative Dentistry Department, Watim Dental College, Rawalpindi, from 1 st March to 31 August 2018. Materials and Methods: Sixty patients who were fulfilling the inclusion criteria were selected. Two groups were made Group 1 and Group 2. The patients were divided into these groups based on table of random numbers. Single blind technique was followed while dividing the patients. Group 1 patients had ledermix placed into the tooth and Group 2 patients had no intracanal medicament placed into the tooth. Patient pain score was recorded after 48 hrs using Visual Analogue Scale. SPSS version 23 was used to analyze the data. Results: Mean inter-appointment pain was 3.23+-1.43 for Ledermix (Group-1) and for no intracanal medicament (Group 2); the mean inter-appointment pain was 5.87+-1.30. A statistically significant difference was recorded with a p-value of 0.005. Conclusion: Patients in which Ledermix was placed as an intracanal medicament experienced significantly less inter-appointment pain as compared to patients having no intracanal medicament (p=0.005) at 48 hours. Hence, ledermix can be effectively used as an intracanal medicament to reduce inter-appointment pain for patients seeking endodontic treatment for acute periapical periodontitis in routine clinical settings.

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