Muhammad Imran Qadir, Khizar Abbas, Rahma Hamayun, Muhammad Ali.
Analgesic, anti-inflammatory and anti-pyretic activities of aqueous ethanolic extract of Tamarix aphylla L. (Saltcedar) in mice.
Pak J Pharm Sci Jan ;27(6):1985-8.

The objective of the study was to investigate the analgesic, anti-inflammatory and anti-pyretic activity of aqueous ethanolic extracts of Tamarix aphylla. The powdered plant was extracted by the method of cold maceration using aqueous ethanol (70:30) as solvents. Analgesic activity was assessed by Eddy’s hot plate method, formalininduced paw licking and acetic acid-induced writhing in mice. Anti-inflammatory activity was evaluated by carageenaninduced mice paw edema. The anti-pyretic activity was determined by yeast-induced pyrexia in mice. The aqueous ethanolic extract of Tamarix aphylla showed 42% inhibition (p<0.005) of acetic acid- induced writhing, 63% reduction (p<0.005) in formalin-induced paw licking, and 42% increase (p<0.05) in reaction time as compared to normal control. The extract did not show significant anti-inflammatory activity. However, it showed significant antipyretic effect (p<0.005). The results of this study demonstrate that aqueous ethanolic extract of Tamarix aphylla exhibit analgesic and antipyretic activity but lacks anti-inflammatory activity.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com