Mehwish Malik, Samina Irshaad, Nadia Ahmed Bokhari, Wardah Ajaz Qazi, Asia Raza, Kanwal Bashir.
Effects of oral fluids and intravenous fluids in the improvement of amniotic fluid index during third trimester of pregnancy.
Pak Armed Forces Med J Jan ;71(1):179-83.

Objective: To assess the effects of oral fluids and intravenous fluids in terms of frequency of improving Amniotic Fluid Index during third trimester of pregnancy having oligohydramnios. Study Design: Comparative prospective survey. Place and Duration of Study: Obstetrics and Gynaecological Department of Fauji Foundation Hospital Rawalpindi, from Apr 2018 to Oct 2018. Methodology: A total of 100 patients with singleton pregnancy (50 in each group) at gestational age of 28-37 weeks and AFI of 5cm or less than 5cm were included. Non probability consecutive sampling technique was used. Ethics approval from hospital ethical committee and research board was taken. Patients were randomized into 2 groups (50 patients each) by lottery method. Group A was instructed to drink 2 liters of water per day for a time period of seven days and patients ingroup B was given 2 liters of 5% D/W which was in addition to their normal fluids intake. Amniotic fluid index was measured pre hydration and post hydration in both groups. Data was analyzed using SPSS-21.Results: Mean age of the patients was 33.62±5.45 years and 34.70±4.76 years for groups A and B respectively. In group A and group B mean gestational age was 34.28±1.85 weeks vs 34.32±1.82 weeks. In group A, 44(88%) while in group B,37(74.0%) patients were of para 0-3 while para 4-7 were 6 (12.0%) in group A and 13(26%) in group B. In group A 36(72%) patients although in group B,34 (68%) were of gravida 1-4. In group A and group B,14(28%) vs 16(32%) were of gravida 5-8. Improvement was observed in 39(78%) patients of group A while22(44%) patients of group B (p<0.001). In group A pre-hydration, mean amniotic fluid index level was 4.79±0.53 and in group B 4.87±0.36 (p=0.383). Post-hydration mean amniotic fluid index level was 6.79±1.22 and 5.97±1.37 in group A and B, respectively (p=0.002).Conclusion: Oral hydration of gestational women is more effective as compare to intravenous hydration in terms of frequency of improving Amniotic Fluid level during third trimester of pregnancy having oligohydramnios.

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