Kashif Zafar, Muhammad Wali, Shoaib Sarwar, Asim Iqbal, Naveed Iqbal, Nida Tasneem.
Frequency of Raised C-Reactive Protein in Acute Heart Failure.
J Sharif Med Dent Coll Jan ;7(02):71-4.

Objective: To determine the C-reactive protein (CRP) levels in patients presenting with acute heart failure. Methodology: This cross-sectional study was conducted at Punjab Institute of Cardiology, Lahore for a period of six months after approval from the Ethical Review Committee of the Institution. Three hundred and forty five patients were enrolled in this study by non-probability consecutive sampling technique. Patients of either gender having age 18-60 years who presented in the emergency department with acute heart failure within 12 hours were included in this study. After informed consent, their venous blood samples were drawn for the measurement of CRP levels. All the data was collected on a predefined proforma. The data was entered and analyzed in Statistical Package for the Social Sciences (SPSS) version 25.0. Results: The mean age of patients was 45.51+/-10.64 years. There were 192(55.7%) males and 153(44.3%) females. The mean duration of heart failure was 6.46+/-3.53 hours. The mean CRP in the study patients was 6.27+/-4.70 mg/L. One hundred and ninety two (55.7%) patients had raised CRP while 153(44.3%) patients had normal CRP levels. Conclusion: Increased CRP levels were seen in a higher number of patients with acute heart failure. This may be established as a significant risk factor for in-hospital mortality due to heart failure. Keywords: Heart failure. C-reactive protein. Inflammation.

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