Anikah Kanwal, Shazia Khalid Khan, Uzma Altaf, Alia Zainab, Uzma Aziz, Farhat Naz.
Frequency of postpartum haemorrhage after delivery in females presenting with hepatitis C virus.
J Allama Iqbal Med Coll Jan ;19(4):821-25.

Background: Hepatitis C virus (HCV) causes an infectious disease Hepatitis C, which primarily affects liver. Its prevalence in pregnant women is projected to be between 1 and 8%, worldwide. Individuals with HCV infection have an enhanced risk for haemorrhage due to effects of HCV on coagulation profile and platelets. In pregnancy-associated with HCV infection, multidisciplinary management is required due to potential risk of bleeding complications. Objective: To assess the frequency of postpartum hemorrhage after delivery in females presenting with hepatitis C virus. Methods: This study involved 250 HCV positive pregnant women of any parity aged between 20-40 years presenting after ≥ 37 completed weeks of gestation for delivery. Outcome variable was frequency of postpartum hemorrhage. Every patient was asked to give a written informed consent. Results: The gestational age ranged from 37 weeks to 42 weeks with a mean of 38.62±1.58 weeks. The parity of the patients ranged from 1 to 5 with 32.0% primiparas, 28.0% multiparas (≤3) and 40.0% grand multiparas (≥ 4). 189 (75.6%) patients developed postpartum hemorrhage. No statistically significant difference was observed in the frequency of postpartum hemorrhage across age (p=0.994), gestational age (p=0.773) and parity (p=0.981) groups. Conclusion: The postpartum hemorrhage frequency was found to be 75.6% amongst HCV positive pregnant women. Key Words: HCV Positive Pregnancy, Postpartum Hemorrhage, Hepatitis C in Pregnancy

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