Muhammad Zafar Iqbal Shahid, Faizan Majeed, Tanveer Haider.
Efficacy of corticosteroid injection in de quervain\'s disease.
J Allama Iqbal Med Coll Jan ;19(4):883-8.

Objective: To assess the long term effectiveness of corticosteroid injection for pain relief in De Quervain's disease with the hypothesis that steroid injection have long term lasting effect. Methods: This prospective case series study was carried out at department of Orthopedic Surgery Services Hospital, Lahore from Feb, 2019 to Jan, 2020 on OPD basis. A total number of sixty patients were included in the study. After approval from hospital ethical committee each patient was injected with 40mg Triamcinolone with 2% lignocaine. These patients were followed up at interval of 1st, 4th, 6th, 8th week and thereafter at 6months and then at 1 year. Each patient was assessed by VAS score and Finkelstein test. Data analysis was done through SPSS version 20. Chi Square test was used for Finkelstein test and t test was used to compare VAS score among patients with positive and negative Finkelstein test. A p-value of <0.005 was considered as significant. Results: Among these 60 patients there were 83.3% were females and 16.7% were males with a male to female ratio of 1:5. Mean age was 37 + 8.7 years with age range was 25 years to 50 years. Right hand was involved in 73.3% patients while the remaining 26.7% patients had left hand involved. These patients were having symptoms for the last 4-6 weeks. Diagnosis of the De Quervain's disease was based upon the history and positive Finkelstein test. At 4th week 91.6% were symptom free and only 5 patients (8.4%) had recurrence. At the end of final follow up 90.0% patients were symptom free and 10.0% did not respond to the corticosteroid injection and they required surgery. No adverse effects were noted except in 15.0% patients there was hypopigmentation at the site of injection which resolved after 6 weeks without any medication. Conclusion: In our study corticosteroid injection has success rate of 90% as initial treatment modality. It is recommended as treatment of choice for this disease. One or two injections of corticosteroids results in significant improvement in sign and symptoms of de Quervain's disease.

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