Shaiqa Mufti, Kehkashan Tahir, Atif Shehzad, Syed Ahmad Kazmi, Asma Nasir, Umara Siddique.
Association of Serum Ferritin Levels and Non-Cicatricial Alopecia in Females.
J Pak Society Int Med May ;2(1):51-4.

Objective:To find the association between serum ferritin levels and non-ciatricial alopecia in females. Methods: 109 premenopausal women, fulfilling the inclusion and exclusion criteria, referred to Dermatology OPD, were enrolled during a period of one year . History taking and physical examination were done and related forms were completed. Aclotted sample of blood was taken for measurement of serum ferritin level and haemoglobin level. Results: Mean age of patients was 26.79+- 6.962. Three clinical sub-types were noted i.e. out of total patients of non-scarring alopecia, 71 were suffering from chronic telogen effluvium (CTE), 23 from alopecia areata (AA) and 15 from androgenetic alopecia (AGA). Among these 109 females, 19 (17.4 %) had optimal serum ferritin levels and 90 (82.6 %) had suboptimal serum ferritin levels. Patients with non-scarring alopecia have significantly lower value of serum ferritin (p=0.002). Among different types of non scarring alopecia CTE had altogether lower estimations of serum ferritin ( p=0.019). The values of haemoglobin were significantly lower in most (75.2%) of the patients. Conclusion: There is statistically significant association between suboptimal serum ferritin levels and noncicatricial alopecia, in our selected sample, verifies depleted iron stores as one of the causative factor of nonscarring alopecia.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com