Muhammad Adnan Aslam, Niamat Ali, Zaheer Ahmad, Moazzam Javid, Gauhar Mahmood Azeem, Faisal Maqbool Zahid.
Prevalence of Depression in patients with Migraine - a study from Central Lahore.
Esculapio J Services Inst Med Sci Jan ;15(4):231-6.

Objective: To determine the prevalence of depression in migraine patients and its association with characteristics of migraine and pharmacotherapy. Methods: This cross-sectional-observational study was conducted at outpatient clinic, Neur- ology Department, Services Hospital, Lahore from January 2019 to June, 2019. Three hundred patients of migraine were included in the study. Information collected was comprising of age, address, gender, contact number, HAM-D score. Depression was defined as patients scoring 8 or more on Hamilton Depression rating scale (HAM-D). Severity of migraine was assessed on a Visual Analogue Scale from 0 (no pain) to 10 (most severe pain). Results: Prevalence of depression was much higher than general population (6-30%) up to 52.7%. Severity of depression was evenly distributed among mild 36(12%), moderate 74(24.7%) and severe 48(16%) depression. An association of the attributes pharmacotherapy & severity of pain in migraine with different levels of depression was observed with p-value <0.001. Conclusions: It is concluded that depression is strongly correlated with migraine and severity of migraine headache, average duration of migraine episode, no pharmacotherapy are independent risk factors correlated with migraine.

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