Rabia Channa, Faisal Nadeem, Sabiha Nasir, Muneeb Ullah.
Comparison of Perinatal Outcomes in Growth Restricted Fetuses with Abnormal and Normal Umbilical Artery Doppler at a Tertiary Care Hospital.
J Islamic Int Med Coll Jan ;18(4):262-6.

Objectives: To compare perinatal outcomes in growth restricted Fetuses based on normal and abnormal umbilical artery doppler studies. Study Design: Prospective Cohort Study. Place and Duration of Study: This Study was conducted in Civil Hospital Karachi. Duration of the study was 6 months, from 24 November 2018 to 25 May 2019.Materials and Methods: 232 growth restricted Fetuses were divided into two equal groups, 116 with normal umbilical artery doppler studies (Group A) and 116 with abnormal umbilical artery doppler studies (Group B). Inclusion criteria were pregnant patients with age 20-35 years and excluding malformations. Doppler assessment used 3-5 MHz probe (GE PRO-V, USA) for umbilical artery and vein, noting absent/reversed flow. Follow-up included delivery, neonatal assessment, and mortality recording. Results: The mean age in our study was 28.92 +- 5.71 years, while gestational age was 33.97 +- 2.58 years. The normal umbilical artery doppler group experienced a 14.66% rate of premature deliveries compared to 52.59% in the abnormal group (p-value: 0.0001). NICU admissions were reported at 26.72% in the normal umbilical artery doppler group and notably higher at 76.72% in the abnormal group (p-value: 0.0001). A striking observation was the threefold increase in perinatal deaths within the abnormal umbilical artery doppler group (18.10%) as opposed to the normal group (7.76%) (p-value: 0.024). Conclusion: Adverse perinatal outcomes were associated with abnormal umbilical artery Doppler in Fetuses with growth restriction. Timely preventive measures should be taken to reduce perinatal morbidity and mortality.

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