Abdullah Bin Imaad,Nayab Khan,Rustam Alam Shah,Imaad-ur Rehman.
Congenital bilateral Perisylvian syndrome: a case report.
Pak J Radiol Jan ;33(3):155-8.

Congenital Bilateral Perisylvian Syndrome (CBPS) is a rare brain structural abnormality. The specific anomaly is called polymicrogyria, which is a type of abnormal brain development. In polymicrogyria, the normal process of cortical development is disrupted during the late stages of neuronal cellular migration. This leads to the formation of many small folds on the surface of the brain and abnormal layers of cells on cortical surface. [1,2,3] In CBPS, there are excessive small folds and unusual layers of brain cells in the Sylvian fissures (a specific area of the brain) and the surrounding cortex. [1 ] CBPS can vary in terms of where it occurs in the brain, its symmetry, what causes it, and the specific symptoms it causes. [1] The symptoms experienced by individuals with BPP depend on which part of the brain is affected. In this case, we are reporting the findings of an MRI scan of a 9-year-old boy who has congenital bilateral perisylvian syndrome (CBPS).

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