Ghazanfar Ali Sirhindi, Javed Asif, Shahida Amjad Riaz Shah, Mateen Izhar, Moona Aziz.
Alteration in routine coagulation profile of the patients taking Injectable Contraceptives.
Ann King Edward Med Uni Jan ;10(3):220-1.
The proposed study is aimed to record the coagulation parameters like fibrinogen degradation products (FDPs), fibrinogen levels, thrombin time (TT), Prothrombin time (PT) and activated partial thromboplastin time (APTT). In this study, coagulation parameters were compared in injectable contraceptives and control group. Forty subjects of injectable group with 20 normal females without hormonal contraceptives were included in the present study with a contraceptive duration from 3-18 months. Blood samples were collected for special coagulation parameters. FDPs and TT levels were significantly elevated in subjects using injectable contraceptives as compared to normal control. PT and APTT were not significantly altered by injectable groups, where fibrinogen levels were significantly reduced in injectable group as compared to normal controls.
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