Khalid Masood Gondal, Salman Akhtar, Muhammad Zahid, Syed Tahir Ahmad Shah.
Changing patterns of elective Surgical Interventions in Peptic Ulcer Disease.
Ann King Edward Med Uni Jan ;10(3):247-9.

Recent emergence of effective anti ulcer drugs, Helicobacter pylori eradication therapy and innovation in endoscopic facilities have limited the role of surgical intervention for non complicated and complicated peptic ulcers. Helicobacter pylori therapy has reduced complications and recurrence rates. This study compares changing spectrum of disease in our set up over 20 years in respect to presentation and surgical intervention required. Twenty four patients required elective operations in four years period from 1980 and the number decreased to nine in six years period from 1997. Majority of these patients (93.9%) were male and of 40-50 years age group (51.5%). Gastric outlet obstruction was main problem (66.6%) followed by non healing ulcer (33.3%). The consistently falling rates of presentation and elective operations for acid peptic disease is a good indicator of effective pharmacological treatment.

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