Nabeel H, Shakoori A R.
Histological changes induced by Hexavalent Chromium on kidneys of albino mice.
Pak Postgrad Med J Jan ;14(3):141-24.

The mice of experimental groups (2 weeks, 4 weeks, 6 weeks and 8 weeks) were injected Potassium dichromate (K2Cr2O7) intraperitoneally on alternate days, at the dose of 2mg Cr.VI / Kg of body weight. The drug had resulted in acute tubular necrosis, hypercellularity and congestion of glomeruli. Extensive interstitial hemorrhages were also observed. The Bowman`s space, diameter of the glomeruli had increased. Initially the diameter of nuclei of cell of proximal convoluted tubules had increased but later decreased. The findings were confirmed by morphometry.

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