Roshan Ali Solangi, Gulshan Ali Memon, Farkhanda Jabeen Dahri, Abdul Razaque Raza Qazi, Sikandere Azam Yousifan.
Does every clean surgical wound need antimicrobials?.
Med Channel Jan ;10(3):41-3.

OBJECTIVE: To study the effect of short regimen antibiotic prophylaxis in clean surgical wounds. DESIGN: Double blind observational study. PLACE OF STUDY: Peoples Medical College Hospital, Nawabshah DURATION: From June 2001 - June 2003 (2 years) MATERIAL & METHODS: 243 patients undergoing various clean surgical procedures were included, 123 and 120 patients were allocated to Group-A and Group-B respectively. They were administered three doses of 10 mal Normal Saline and Inj. Cephradine 1gm, 500mg I/V half hour before surgery and at 8th, and 16th hour postoperatively to Group-A and B cases respectively RESULTS: 19 (15.44%) and 17 (14.17%) patients were infected in Group-A and B respectively, overall 36 (14.81%) patients were infected. CONCLUSION: Short term antimicrobial prophylaxis regimen do not possess significantly marked role in preventing clean surgical wound infection. Working condition in respect with. theatre environment, standard of operation theatre, expertise and aseptic measures should be improved to achieve better results.

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