Arifur Rehman Khan, Tariq Azam Siddiqui, Muhammad Zahid Ullah, Nadeem Ahmed, Muhammad Musharaf, Shaukat Ali, Bushra Osmany.
Coronary Artery Bypass Grafting in young adults.
Pak J Cardiol Jan ;15(2):74-8.

Atherosclerotic coronary artery disease in younger patients is different than that in older age group. As a result Coronary Artery Bypass Grafting (CABG) among such patients carries other considerations. The purpose of this study was to document the early surgical results of patients under the age of 35 years, under going CABG in mixed Pakistani population. Secondly, to examine the etiological factors and the issues related to psychological, social and sexual disturbances after surgery. Finally, to recommend a strategy for future management. Methods. Hospital data of all the patients under the age of 35 years undergoing CABG from January 2001 to December 2002, at National Institute of Cardiovascular Diseases, Karachi, was scrutinized. Various parameters were compared with those of older patient population, reported by our centre, being taken as a control. Results: A total of 87 patients underwent surgery, 82 were males and 5 were females. The age range from 21 to 35 years. Risk factors included family history of coronary Artery disease in 74 percent, smoking in 86 percent, familial hypercholesterolemia in 29 percent, diabetes mellitus in 59 percent and hypertension in 42 percent. There were two hospital deaths. Post-operative morbidity included cardiac (17 percent), pulmonary (10 percent), infections (6 percent) and renal (1 percent). Conclusion-Short term results in this patient population were comparable to those of older age group. Psychosocial and sexual dysfunction were more prominent in this patient population. Now compliance for secondary prevention was more prevalent in this age group. An organized, multi disciplinary approach is required to tackle various issues of this age group.

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