Shamsul Arfeen Khan, Hasan Ali, Khemomal A Karira, Rashida Qasim, Mujtaba Farooq Rana.
Hypercalciuria; induced by drinking carbonated beverages.
Professional Med J Jan ;12(1):52-8.

Objective: To assess the short term effects on urinary calcium excretion of carbonated beverages. Design: Case control study. Setting: Department of Biochemistry, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. Period: From Oct 2001 to Dec 2004 Materials & Method: Fifty-one normal subjects of either sex age ranged from 20-40 years, with habitual users of carbonated beverages were selected for the study. Their fasting and post-beverage urine samples were analyzed for calcium excretion. Results: Out of 51 patients we have observed a significant increase in urinary calcium excretion from that of both caffeinated and non-caffeinated beverages in male subjects (P<0.001). In females more calciuria was found in their fasting samples a reason of non-significant results after beverages consumption. Conclusion: The excess calciuria is confined to both caffeinated and non-caffeinated beverages in males. It is suggested that habitual use must be restricted to prevent bone resorption and an early osteoporosis.

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