Mubashir A Sheikh, Bilquees Begum, Muhammad Shoaib Khan, Aftab Turabi, Ahmed Danyal, Saud Hasan Zaidi.
Azoospermia & Oligozoospermia; semen and hormonal analysis of patients.
Professional Med J Jan ;12(1):80-4.

Objectives: To differentiate and analyses different groups of patients according to abnormalities of azoospermia and oligozoospermia. Design of study: Prospective study Setting: Clinical pathology Laboratory Jinnah Postgraduate Medical Centre Karachi. Period: 1999 to 2003. Material & Method: Analysis of semen volume, liquefaction time, pH and sperm concentration were carried out for 150 men from infertile couples alongwith measurement of hormone levels. 50 normal fathers with proven fertility were taken as control. Results: 33.33% patients showed azoospermia (A), 50 cases (33.33%) had oligozoospermia (B), 20 cases (13.33%) were asthenozoospermic (C) and 30 cases (20%) were found to be normozoospermic (D). The hormonal profile showed normal or low levels of testosterone while FSH and LH levels indicated inverse/negative correlation to sperm concentration, whereas no significant relationship between serum prolactin and semen density was detectable between different groups. Conclusions: Azoospermic and oligozoospermic subjects are accompanied by a significant rise in FSH levels, and decrease in serum testosterone level. The need for measuring prolactin levels in the evaluation of male infertility is unnecessary.

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