Anwar M, Naqvi Sqh, Kehar S Imdad, Jamal Q, Naqvi SQH.
Histopathological correlation of Endometrial curettage with abnormal Uterine bleeding pattern.
J Surg Pak Jan ;9(2):21-4.

OBJECTIVE: To determine the histopathological pattern of lesions associated with abnormal uterine bleeding in different age groups. DESIGN: A cross sectional study of 500 randomly selected specimens. PLACE: Department of Pathology, Basic Medical Sciences Institute, Jinnah Post Graduate Medical Center Karachi. DURATION: January 2002 to December 2003. METHODS: 500 formalin fixed paraffin embedded blocks were retrieved and 5mm thick sections were cut and stained with haemotoxylin and eosin, periodic acid-scher trichrome & reticulin. The other additional information collected was age, pattern of bleeding, and clinical findings. RESULTS: Of 500 specimens examined, endometrial pathology was detected in 164 cases. The most frequent histopathological change was endometrial hyperplasia observed in 103 patients (62.8%). 26 (15.8%) out of 164 were associated with malignant changes and the maximum number of cases Le. 64 were found in 31-40 years age group. CONCLUSION: The current study emphasizes the necessity of D&C before the age of 40 years in patients presenting with abnormal uterine bleeding.

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