Mumtaz Ahmed, Tariq Masood Malik, Saeed Afzal, Azhar Mubarik.
Clinicopathological study of 762 ovarian neoplasms at Army Medical College Rawalpindi.
Pak J Pathol Jan ;15(4):147-52.

A retrospective cross sectional study was carried out at Pathology Department of Army Medical College Rawalpindi from January 1995 to December 2003 to see the morphological pattern of benign and malignant ovarian tumours. A total of 762 ovarian tumours were studied during a period of nine years. Of these, 498 (65.35%) were benign, 33 (4.33%) of borderline malignancy and 231 (30.31%) were malignant. The relative frequency of malignant ovarian tumours of all gynaecologic malignancies was found to be 24.01%. The age range of ovarian tumours was 9 to 80 years. Maximum number (66.88%) of benign tumours were in younger patients (<40 years), whereas majority of malignant tumours (65.83%) were seen in 5th to 6th decades. Histologically, the major categories included surface epithelial tumours 527 (69.16%), germ cell tumours 201 (26.37%), sex cord- stromal tumors 34 (4.46%) and miscellaneous 4 (0.52%). Amongst the malignant tumours, the most common entity was serous cystadenocarcinoma (46.75%), followed by mucinous cystadenocarcinoma (22.94%), dysgerminoma (6.06%), granulosa cell tumours (5.62%) and endometrioid carcinoma (4.76%). In this study, ovarian tumours were seen in younger age and serous tumours were relatively more common than experienced in the western world. Overall trends for other malignancies are more or less similar to other Pakistani studies except for mucinous carcinoma.

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