Khalid A Dahiyat.
Does nitric oxide inhalation need to be reassessed?.
Ann King Edward Med Uni Jan ;12(1):42-6.

Background: Inhaled nitric oxide is a drug which has been given FDA approval in 1999 but was not found prior to approval to be safe for use in premature neonates. Aim: To review and assess the studies which was done prior to its approval in order to find out what evidences the approval by the FDA was based on. Methods: A thorough search of the electronic data-base, Medline, Embase, Cinahl, Google. Conclusion: The use of this drug in treatment of the Pulmonary hypertension in premature babies is still contraversial and hold a serious untoward effects on the health, it should only used as the last ditch.

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