Giasuddin Ahmed, Md Shahdat Hossain, Yearul Kabir, Syeda Shamim Jahan.
Effects of Hilsha Ilisha fish oil, soybean and palm oil on the serum and liver lipids of experimentally-induced hypercholesterolemic rats.
Pak J Med Res Jan ;45(2):53-8.

Aims: To see the effects of Hilsha ilisha fish oil, soybean and palm oils on the lipid profile of experimentally induced hypercholesterolemic rats. Methods: The hypercholesterolemic rats were supplemented with 10% Hilsha fish oil, 10% soybean oil, 10% palm oil and 7.5% Hilsha oil for 28 days. Serum and liver lipids and cholesterol excretion through feces were determined. Results: The serum and liver cholesterol of 10% Hilsha fish oil-fed rats decreased significantly (P<0.05) when compared to 10% soybean and/or palm oil fed rats. There was no significant difference in serum cholesterol level between the rats fed with 10% soybean oil and 10% palm oil. The fall in serum total cholesterol in each case paralleled with the fall in serum LDL-cholesterol and an increase in HDL-cholesterol level. Serum total lipids and phospholipid significantly lowered in rats fed with 10% Hilsha oil, when compared with other groups. The Hilsha oil fed rats also excreted the highest amount of fecal cholesterol when compared with rats fed with soybean oil, palm oil, and/or Hilsha fish oil. Conclusion: The present study shows that Hilsha ilisha fish oil is more effective in reducing the serum and liver cholesterol than soybean and palm oil, though both soybean and palm oil are also effective in reducing serum and liver cholesterol.

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