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icon Hepatitis C Cured Rate

icon Re: Hepatitis C Cured Rate

icon Re: Hepatitis C Cured Rate

icon Re: Hepatitis C Cured Rate

icon Re: Hepatitis C Cured Rate

icon Re: Hepatitis C Cured Rate

icon Re: Re: Hepatitis C Cured Rate

quote:
docosama wrote:
Sir, i wanted to know what is the reference of treatment for Acute HCV you have mentioned?


http://www.apgo.org/bookstore/index.cfm?doc=Sexually%20Transmitted%20Infections

Regimen for acute HCV is:

IFNa-2b daily for 4 weeks and then 3 times a week for additional 20 weeks. 98% of the treated patients were virologic responders (with undetectable levels of HCV RNA in serum and normal ALT) compared to only 30% of untreated patients. Response was not affected by viral genotype, patients's sex or the mode of transmission.

There's another more recent article in Hepatology May 2004 which is not yet available.

[Edited by chameed on 05-16-2004 at 01:37 AM GMT]

[Edited by chameed on 05-16-2004 at 01:52 AM GMT]

icon Re: Hepatitis C Cured Rate

icon Re: Re: Hepatitis C Cured Rate

quote:
drkhawaja wrote:
I am afraid we are drifting from our case in discussion. The young man has raised certain issues relating to his sickness. There is no argument about chronic hepatitis C in his case. To me some of the problems which need to be answered ( & for which we can share our expertise including issues of cost effectiveness) are as follows,
1. The basic investigations needed in evaluating his liver disease?
2. Is liver biopsy absolutely necessary? (? cost in Pakistan.)
3. Availability of newer tests to assess liver fibrosis without biopsy.
4. Coorelation of viral load with the severity of liver damage.
5. Factors adversely affecting response to therapy eg diabetes, obesity,alcohol,Fe load etc.
6. Type and duration of treatment for our case ie genotype 3.
7. How to follow response during and after completing therapy.

I hope our discussion and exchange of ideas stay healthy , clinical and supported by scientific data.
3.


Who is 'we' and 'drifting? from what? I gave some useful info to the young man so h can make an informed decision. I must commend his doc for recommending the treatment.

If every time you give your opinion and you have to back it up with literarture, that is your insecurity and I can't help you with that. You wanna do a liver biopsy, go ahead and do it but don't tell me that liver biopsy is justified at this stage of the disease. Rest of your questions are immaterial as far as prognosis is concerned because the prognosis is unknown.

icon Re: Hepatitis C Cured Rate

icon Re: Re: Hepatitis C Cured Rate

quote:
docosama wrote:
What is the evidence of Acute Hepatitis C in this patient? One should know that Acute Hepatitis due to HCV is very rare.


No evidence at all, but what led to the investigation and discovery of positive HCV? The original question was about a second opinion regarding the appropriateness of the therapy prescribed by his physician and not how to pass a multiple choice exam. Posting a page out of a textbook is simply juvenile and lack of experience.

You are somewhat right about Acute Hepatits C being a rare phenomenon but that may be because the disease is insidious for many years and symptoms may not exist. That's another reason to treat with whatever is available because in this case, the duration is unknown.


[Edited by chameed on 06-04-2004 at 11:48 AM GMT]

icon Re: Hepatitis C Cured Rate

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